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By Marc E. de Broe, Patrick C. D’Haese (auth.), Marc E. de Broe, Jack W. Coburn (eds.)

` ... the cloth provided offers worthy info about the organic results and scientific syndromes linked to aluminum publicity. This quantity might be helpful for college kids and nephrologists who're attracted to furthering their figuring out of the area.'
Dialysis and Transplantation, 20/1, January 1991

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Pharmacol Ther 29: 255. 10. Martin RB, 1986: Bioinorganic chemistry of metal ion toxicity. Metal Ions Bioi Syst 20: 21. 11. Martin RB, 1986: The chemistry of aluminum as related to biology and medicine. Clin Chern 32: 1797. 12. Martin RB, 1988: Bioinorganic chemistry of aluminum. Metal Ions Bioi Syst 24: Chapter 1. 13. Martin RB, 1984: Bioinorganic chemistry of calcium. Metal Ions Bioi Syst 17: 1. 14. Margerum DW, Cayley GR, Weatherburn DC, and Pagenkopf GK, 1978: Kinetics and mechanisms of complex formation and ligand exchange.

These clinical observations do not offer a clue as to why most patients endure high doses for a long period of time with an acceptable rise in serum AI, whereas a minority apparently absorbes Al from its hydroxide to a large extent. To solve this interindividual variation, research has to be performed into the mechanism of Al transport through the intestinal mucosa. This subject is dealt with in Section 4. 44 Aluminum absorption in non-renal patients Data on Al absorption in other than renal patients are scarce so far.

Martin RB, 1985: Nucleoside sites for transition metal ion binding. Accts Chern Res 18: 32. 40. Karlik SJ, Elgavish GA, and Eichhorn GL, 1983: Multinuclear NMR studies on AI(III) complexes of ATP and related compounds. J Am Chern Soc 105: 602. 41. Scheller KH, Scheller-Krattiger V, and Martin RB, 1981: Equilibrium in solutions of nucleosides, 5' -nucleotides and dienPd2 +. J Am Chern Soc 103: 6833. 26 42. Scheller KH, Hofstetter F, Mitchell PR, Prijs B, and Sigel H, 1981: Macrochelate formation in monomeric metal ion complexes of nucleoside 5' -triphosphates and the promotion of stacking by metal ions.

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