Download Advances in Nutrition and Cancer 2 by Peter Greenwald (auth.), Vincenzo Zappia, Fulvio Della PDF

By Peter Greenwald (auth.), Vincenzo Zappia, Fulvio Della Ragione, Alfonso Barbarisi, Gian Luigi Russo, Rossano Dello Iacovo (eds.)

This quantity comprises contributions awarded on the moment foreign Sym­ posium on food and melanoma, held in Naples, Italy, in October 1998 on the nationwide Tumor Institute "Fondazione Pascale." through the convention, specialists from diversified disciplines mentioned pivotal and well timed matters at the interactions among human nutrients and the advance of malignancies. evaluating the subjects of this assembly with these mentioned on the First Sympo­ sium in 1992, the most important clinical developments definitely derive from the vast use of molecular ways to accomplish examine in food. in addition, the elemental commentary of R. Doll and R. Peto (1981), which recommended that no less than 35% of all cancers (with huge ameliorations between diversified tumors) can be avoided by way of nutritional regimens, has been definitively proven through epidemiological reviews. nevertheless, the relationships among vitamin and melanoma are rather tricky and complicated; it truly is tough, and whilst now not methodologically right, to lessen them to basic phrases. Metabolic and hormonal elements, contaminants and organic brokers, and deficiency of particular protecting foodstuff are all items of an identical puzzle.

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The food frequency questionnaire had been specifically developed for the Italian dietary pattern and tested in a pilot phaseY Dietary information on the frequency of consumption of more than 120 foods and beverages obtained by this questionnaire, has been checked, coded, computerised by optical reading and then transformed into estimates of intake of 40 nutrients according to specifically developed Italian Food Tables. 13 A standardised life style questionnaire (specifically printed in two versions for men and women) has also been filled by each participant; detailed information has been collected on reproductive history, physical activity, smoking history, alcohol drinking, medical history, occupation, education level, and other socio-economic variables.

Potter ID. and McMichael Al Diet and cancer of the colon and rectum: a case-control study. J Nat! Cancer Inst. 1986;76:557-569. Nutritional Factors in Human Cancers 39 33. , and Stanish W. Energy intake: its relationship to colon cancer risk. J Nat! Cancer Inst. 1987;78:853-861. 34. , and West D. Dietary epidemiology of cancer of the colon in western New York. Am J Epidemiol. 1988;128:490-503. 35. , and Williamson RC Sugar, fat, and the risk of colorectal cancer. Br Med J (Clin Res Ed). 1985;291:1467-1470.

Populations share more continental habits, high consumption of butter and dairy products, but also include a large proportion of migrants from Southern Italy) will allow the investigation of a wide range of dietary patterns, representative of the major areas of the country. At the same time, a high variability (Table 1) in cancer incidence and mortality is present within Italy, ranging from nearly 2-fold differences for cancers of the colonrectum, breast, and lung to a 3-fold ratio for upper aereo-digestive tract cancers in males.

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